Go to the location where you installed it and right click diablo.exe; Go to the compatibility tab and select Reduced Color Mode, set it to 16 bits. Play with double click. OPTIONAL: Install Diablo v1.09 Patch if you wish it fixes several bugs. NOTE: The ISO needs to remain mounted while playing. Tested working on Windows 10. Diablo ® II: Lord of Destruction ® is being downloaded! If your download didn't start, try again. Diablo 2 disc 3.iso download. Wow disc.iso download. Download 1 file. ITEM TILE download. Download 1 file. Download 1 file.
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No-CD & No-DVD Patch troubleshooting: The most common problem getting a No-CD/No-DVD patch to work is ensuring that the No-CD/No-DVD patch matches you're game version, because the games exe is changed when a patch update is applied previous versions won't work.
If its an older game you are playing and you are running Windows 7 or Windows 8 it may not work, if you right click the .exe file and choose Properties and then Compatibility you can change this to run in Windows 98/ Windows 2000 etc. You can find more information on the Beginners Help page here